SCHEMBL29933707

SCHEMBL29933707

CC(C)(C)OC(=O)N1CC[C@@H](Nc2ccnc3ccc(F)cc23)C1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.57
PIK3CD O00329 3/20 0.53
PIK3CA P42336 2/20 0.49
USP30 Q70CQ3 5/20 0.47
CNR1 P21554 3/20 0.47
CCNT1 O60563 2/20 0.46
CDK9 P50750 2/20 0.46
GFER P55789 1/20 0.45
DNMT3A Q9Y6K1 1/20 0.44
BRD4 O60885 1/20 0.44
PIK3CB P42338 1/20 0.43
PIK3CG P48736 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28834220 1.00 IDO1 (0.57) IDO1PIK3CDPIK3CAUSP30CNR1
SCHEMBL28834221 1.00 IDO1 (0.57) IDO1PIK3CDPIK3CAUSP30CNR1
SCHEMBL23360131 0.94 IDO1 (0.61) IDO1PIK3CDPIK3CACNR1CCNT1
SCHEMBL29862762 0.94 IDO1 (0.61) IDO1PIK3CDPIK3CACNR1CCNT1
SCHEMBL30958645 0.89 PIK3CD (0.52) IDO1PIK3CDPIK3CAUSP30CNR1
SCHEMBL29933711 0.89 PIK3CD (0.52) IDO1PIK3CDPIK3CAUSP30CNR1
SCHEMBL29933511 0.89 CNR1 (0.55) IDO1PIK3CDPIK3CAUSP30CNR1
SCHEMBL28833982 0.89 CNR1 (0.55) IDO1PIK3CDPIK3CAUSP30CNR1
SCHEMBL29933647 0.88 PIK3CD (0.55) IDO1PIK3CDPIK3CAUSP30CNR1
SCHEMBL28834195 0.88 PIK3CD (0.55) IDO1PIK3CDPIK3CAUSP30CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL IDO1 1364/4885PIK3CD 641/4885PIK3CA 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.