Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501620 | 1.00 | KDM4E (0.34) | KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL17821045 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL14909586 | 0.74 | CHRNB2 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL1663512 | 0.73 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4531684 | 0.73 | ALDH1A1 (0.48) | KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL17820134 | 0.73 | ALDH1A1 (0.33) | KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL29935900 | 0.73 | ALDH1A1 (0.48) | KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL17819606 | 0.73 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL17820777 | 0.73 | CYP3A4 (0.47) | — | |
| SCHEMBL17820897 | 0.72 | TRIM24 (0.53) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |