Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ATP6V1B1 | P15313 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29934050 | 0.91 | DRD2 (0.47) | DRD2GAAHPGDTAS1R3TAS1R1 | |
| SCHEMBL7321932 | 0.76 | ALOX5 (0.57) | DRD2GAAHPGDALOX5KDM4E | |
| SCHEMBL29875286 | 0.76 | ALOX5 (0.50) | DRD2GAAHPGDALOX5KDM4E | |
| SCHEMBL977577 | 0.76 | ALOX5 (0.50) | DRD2GAAHPGDALOX5KDM4E | |
| SCHEMBL19182733 | 0.75 | DRD2 (0.46) | DRD2GAAHPGDALOX5KDM4E | |
| SCHEMBL28861684 | 0.75 | ALOX5 (0.44) | DRD2GAAHPGDTAS1R3TAS1R1 | |
| SCHEMBL1121804 | 0.75 | DRD2 (0.46) | DRD2GAAHPGDALOX5KDM4E | |
| SCHEMBL22931310 | 0.75 | DRD2 (0.49) | DRD2GAAHPGDALOX5KDM4E | |
| SCHEMBL1464939 | 0.73 | HPGD (0.53) | DRD2GAAHPGDTAS1R3TAS1R1 | |
| SCHEMBL19780891 | 0.73 | GAA (0.48) | DRD2GAAHPGDALOX5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879790-B | Amide micromolecule organic compound with indole or indole analogue as mother nucleus structure, application and preparation method thereof | 华东师范大学 | 2022-09-20 | — | — | CN | disclosed |