Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 3/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16801822 | 1.00 | KDM4E (0.51) | KDM4EHIF1ATDP1SLC1A3SLC1A2 | |
| SCHEMBL31520048 | 1.00 | KDM4E (0.51) | KDM4EHIF1ATDP1SLC1A3SLC1A2 | |
| SCHEMBL148492 | 1.00 | KDM4E (0.51) | KDM4EHIF1ATDP1SLC1A3SLC1A2 | |
| SCHEMBL31520056 | 1.00 | KDM4E (0.51) | KDM4EHIF1ATDP1SLC1A3SLC1A2 | |
| SCHEMBL145723 | 1.00 | KDM4E (0.51) | KDM4EHIF1ATDP1SLC1A3SLC1A2 | |
| SCHEMBL17623477 | 0.84 | RXFP1 (0.39) | KDM4EHIF1ATDP1PKMCASR | |
| SCHEMBL20340876 | 0.84 | RXFP1 (0.39) | KDM4EHIF1ATDP1PKMRXFP1 | |
| SCHEMBL24380208 | 0.82 | KDM4E (0.54) | KDM4EHIF1ATDP1SLC1A3SLC1A2 | |
| SCHEMBL19273914 | 0.82 | KDM4E (0.54) | KDM4EHIF1ATDP1SLC1A3SLC1A2 | |
| SCHEMBL31469728 | 0.82 | KDM4E (0.54) | KDM4EHIF1ATDP1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301790-A1 | SUNSCREENS DERIVED FROM KYNURENINES AND OTHER UV-ABSORBING OXIDIZED AMINO ACIDS BOUND TO PEPTIDES OR POLYMERS | The Trustees Of Princeton University (US) | 2024-01-10 | — | — | EP | claimed |
| WO-2022197819-A1 | SUNSCREENS DERIVED FROM KYNURENINES AND OTHER UV-ABSORBING OXIDIZED AMINO ACIDS BOUND TO PEPTIDES OR POLYMERS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2022-09-22 | — | — | WO | claimed |
| US-20240307285-A1 | SUNSCREENS DERIVED FROM KYNURENINES AND OTHER UV-ABSORBING OXIDIZED AMINO ACIDS BOUND TO PEPTIDES OR POLYMERS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2024-09-19 | — | — | US | disclosed |
| EP-4301790-A1 | SUNSCREENS DERIVED FROM KYNURENINES AND OTHER UV-ABSORBING OXIDIZED AMINO ACIDS BOUND TO PEPTIDES OR POLYMERS | The Trustees Of Princeton University (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022197819-A1 | SUNSCREENS DERIVED FROM KYNURENINES AND OTHER UV-ABSORBING OXIDIZED AMINO ACIDS BOUND TO PEPTIDES OR POLYMERS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2022-09-22 | — | — | WO | disclosed |