SCHEMBL148492

SCHEMBL148492

NC(CC(=O)c1ccccc1NC=O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.51
HIF1A Q16665 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
SLC1A3 P43003 4/20 0.41
SLC1A2 P43004 4/20 0.41
SLC1A1 P43005 4/20 0.41
GRIK1 P39086 4/20 0.40
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
PTGS1 P23219 1/20 0.40
XIAP P98170 1/20 0.40
SLC7A5 Q01650 1/20 0.40
CASR P41180 1/20 0.39
KMO O15229 3/20 0.39
GRIK2 Q13002 2/20 0.39
GRM2 Q14416 1/20 0.39
GRM3 Q14832 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16801822 1.00 KDM4E (0.51) KDM4EHIF1ATDP1SLC1A3SLC1A2
SCHEMBL31520048 1.00 KDM4E (0.51) KDM4EHIF1ATDP1SLC1A3SLC1A2
SCHEMBL29934103 1.00 KDM4E (0.51) KDM4EHIF1ATDP1SLC1A3SLC1A2
SCHEMBL31520056 1.00 KDM4E (0.51) KDM4EHIF1ATDP1SLC1A3SLC1A2
SCHEMBL145723 1.00 KDM4E (0.51) KDM4EHIF1ATDP1SLC1A3SLC1A2
SCHEMBL17623477 0.84 RXFP1 (0.39) KDM4EHIF1ATDP1PKMCASR
SCHEMBL20340876 0.84 RXFP1 (0.39) KDM4EHIF1ATDP1PKMRXFP1
SCHEMBL24380208 0.82 KDM4E (0.54) KDM4EHIF1ATDP1SLC1A3SLC1A2
SCHEMBL19273914 0.82 KDM4E (0.54) KDM4EHIF1ATDP1SLC1A3SLC1A2
SCHEMBL31469728 0.82 KDM4E (0.54) KDM4EHIF1ATDP1SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098007-A1 Compounds and Their Use in Filtering Ultraviolet and/or High-Energy Visible Light SOLIOME INC (US) 2026-04-09 US claimed
EP-3831379-B1 A COMPOSITION CONTAINING NICOTINIC ACID AND/OR NICOTINAMIDE AND/OR TRYPTOPHAN FOR POSITIVELY INFLUENCING THE INTESTINAL MICROBIOTA CONARIS RES INSTITUTE AG (DE) 2025-09-10 EP claimed
EP-4587007-A2 COMPOUNDS AND THEIR USE IN FILTERING ULTRAVIOLET AND/OR HIGH-ENERGY VISIBLE LIGHT Soliome, Inc. (US) 2025-07-23 EP claimed
US-20250213549-A1 COMPOSITION COMPRISING NICOTINAMIDE, NICOTINAMIDE PRECURSORS, NICOTINAMIDE METABOLITES OR COMBINATIONS THEREOF FOR PREVENTING OR REDUCING ONE OR MORE POST-ACUTE SYMPTOMS OF INFECTIOUS DISEASES CONARIS RESEARCH INSTITUTE AG (DE) 2025-07-03 US claimed
EP-4572737-A1 METHODS OF USING A SMALL MOLECULE CHEMICAL COMPOUND TO REDUCE THE APPEARANCE OF RHYTIDS AND WRINKLES Birchbiomed Inc. (CA) 2025-06-25 EP claimed
CN-119894495-A Method for reducing wrinkle and crease appearance using small molecule compounds 伯奇生物医药有限公司 2025-04-25 CN claimed
CN-116087353-B Metabolic identification method for wild cordyceps sinensis and substitute thereof 武汉大学中南医院 2025-04-08 CN claimed
CN-114938659-B Cardiovascular disease onset risk assessment marker based on metabonomics data and application thereof 中国医学科学院阜外医院 2025-03-04 CN claimed
CN-119391580-A Lactobacillus rhamnosus capable of preventing or treating inflammatory bowel disease and promoting digestion and application thereof 内蒙古科拓生物有限公司 2025-02-07 CN claimed
EP-4499059-A1 COMPOSITION COMPRISING NICOTINAMIDE, NICOTINAMIDE PRECURSORS, NICOTINAMIDE METABOLITES OR COMBINATIONS THEREOF FOR PREVENTING OR REDUCING ONE OR MORE POST-ACUTE SYMPTOMS OF INFECTIOUS DISEASES CONARIS research institute AG (DE) 2025-02-05 EP claimed
WO-2016038011-A1 METHODS & COMPOUNDS USEFUL IN HEMATOPOIETIC STEM CELL MEDICINE ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2016-03-17 WO claimed
EP-2995948-A1 Methods and compounds useful in hematopoietic stem cell medicine Ecole Polytechnique Federale de Lausanne (EPFL) (CH) 2016-03-16 EP claimed
WO-2016013017-A1 EX-VIVO INDUCED REGULATORY MESENCHYMAL STEM CELLS OR MYELOID-DERIVED SUPPRESSOR CELLS AS IMMUNE MODULATORS HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD (IL) 2016-01-28 WO claimed
WO-2015091862-A1 SCREENING METHOD IOMET PHARMA LTD (GB) 2015-06-25 WO claimed
US-20140065099-A1 Methods of Treating Mitochondrial Dysfunction ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2014-03-06 US claimed
WO-2012114204-A2 METHODS OF TREATING MITOCHONDRIAL DYSFUNCTION ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) EPFL-TTO (CH) 2012-08-30 WO claimed
US-20100261774-A1 Methods for the modulation of Leishmania major infection in mammals CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2010-10-14 US claimed
US-20090208565-A1 STABILIZED EXENDIN-4 COMPOUNDS ZEALAND PHARMA A/S (DK) 2009-08-20 US claimed
US-20060194719-A1 Stabilized exendin-4 compounds ZEALAND PHARMA A/S (DK) 2006-08-31 US claimed
EP-1369114-A1 Use of tryptophan metabolites as pharmaceutical agents Terness, Peter, Priv. Doz. Dr. (DE) 2003-12-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098007-A1 Compounds and Their Use in Filtering Ultraviolet and/or High-Energy Visible Light UGT8, UGT1A3, FUT5 KDM4E 3137/4885HIF1A 3431/4885TDP1 1560/4885
US-20060194719-A1 Stabilized exendin-4 compounds GLP1R, IAPP, MC4R KDM4E 626/4885HIF1A 2894/4885TDP1 4193/4885
US-20090208565-A1 STABILIZED EXENDIN-4 COMPOUNDS GLP1R, IAPP, MC4R KDM4E 610/4885HIF1A 2857/4885TDP1 4060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.