Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501608 | 1.00 | ALDH1A1 (0.46) | ALDH1A1GFERKDM4EMAPTGAA | |
| SCHEMBL112800 | 0.87 | MC4R (0.47) | ALDH1A1KDM4EMAPTGAATDP1 | |
| SCHEMBL29933818 | 0.87 | MC4R (0.47) | ALDH1A1KDM4EMAPTGAATDP1 | |
| SCHEMBL17108787 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1KDM4ETDP1DRD2DRD4 | |
| SCHEMBL1880665 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1GFERKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL1858409 | 0.83 | SMN1; SMN2 (0.57) | ALDH1A1GFERKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL17108786 | 0.83 | SMN1; SMN2 (0.57) | ALDH1A1GFERKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL17108785 | 0.81 | ACHE (0.50) | ALDH1A1KDM4E | |
| SCHEMBL29934322 | 0.80 | HRH3 (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL114033 | 0.80 | HRH3 (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |