Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 1/20 | 0.65 |
| ▸ | SOD1 | P00441 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | POLA1 | P09884 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sugiol SCHEMBL28605319 | 0.86 | SOD1 (0.58) | KARS1SOD1CYP3A4MAPTMEN1 | |
| Sugiol SCHEMBL17407685 | 0.86 | SOD1 (0.58) | KARS1SOD1CYP3A4MAPTMEN1 | |
| Sugiol SCHEMBL1086916 | 0.86 | SOD1 (0.58) | KARS1SOD1CYP3A4MAPTMEN1 | |
| SCHEMBL18290229 | 0.82 | SOD1 (0.72) | KARS1SOD1CYP3A4MAPTALDH1A1 | |
| SCHEMBL15388986 | 0.82 | CYP3A4 (0.64) | KARS1CYP3A4MAPTMEN1TP53 | |
| SCHEMBL15388987 | 0.82 | CYP3A4 (0.64) | KARS1CYP3A4MAPTMEN1TP53 | |
| SCHEMBL30712349 | 0.78 | SOD1 (0.49) | KARS1SOD1CYP3A4MAPTALDH1A1 | |
| SCHEMBL19786216 | 0.75 | ESR1 (0.42) | KARS1SOD1CYP3A4MAPTMEN1 | |
| SCHEMBL18290200 | 0.74 | SOD1 (0.76) | KARS1SOD1CYP3A4MAPTMEN1 | |
| SCHEMBL29403700 | 0.73 | ESR1 (0.48) | KARS1SOD1CYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |