Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.72 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.46 |
| ▸ | FDPS | P14324 | 4/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sugiol SCHEMBL28605319 | 0.86 | SOD1 (0.58) | SOD1ARCYP3A4MAPTALOX15 | |
| Sugiol SCHEMBL17407685 | 0.86 | SOD1 (0.58) | SOD1ARCYP3A4MAPTALOX15 | |
| Sugiol SCHEMBL1086916 | 0.86 | SOD1 (0.58) | SOD1ARCYP3A4MAPTALOX15 | |
| SCHEMBL18290208 | 0.83 | SOD1 (1.00) | SOD1ARCYP3A4MAPTALOX15 | |
| SCHEMBL18290292 | 0.83 | SOD1 (1.00) | SOD1ARCYP3A4MAPTALOX15 | |
| SCHEMBL31291111 | 0.83 | AR (0.68) | SOD1ARCYP3A4MAPTALOX15 | |
| SCHEMBL29934307 | 0.82 | KARS1 (0.65) | SOD1ARCYP3A4MAPTALOX15 | |
| SCHEMBL30712349 | 0.78 | SOD1 (0.49) | SOD1ARCYP3A4MAPTALOX15 | |
| 18-Hydroxyferruginol SCHEMBL32666150 | 0.77 | KARS1 (0.67) | SOD1CYP3A4MAPTALOX15USP2 | |
| 18-Hydroxyferruginol SCHEMBL18290210 | 0.77 | KARS1 (0.67) | SOD1CYP3A4MAPTALOX15USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |