Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 11/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taraxerone SCHEMBL3155249 | 0.83 | PTPN1 (0.62) | CES2CES1PTPN1F3PNLIP | |
| Taraxerone SCHEMBL23929104 | 0.83 | PTPN1 (0.62) | CES2CES1PTPN1F3PNLIP | |
| SCHEMBL4202103 | 0.80 | PTPN1 (0.71) | PTPN1PTPN2AKR1B10AKR1B1 | |
| 3-Oxo-Erythrodiol SCHEMBL18688302 | 0.75 | CES2 (0.76) | CES2CES1PTPN1F3PNLIP | |
| SCHEMBL13666320 | 0.69 | NOS2 (0.45) | CES2CES1PTPN1F3PNLIP | |
| SCHEMBL18214215 | 0.69 | PTPN1 (0.39) | CES2CES1PTPN1F3PNLIP | |
| SCHEMBL12200228 | 0.69 | NOS2 (0.45) | CES2CES1PTPN1F3PNLIP | |
| SCHEMBL15499352 | 0.69 | NOS2 (0.45) | CES2CES1PTPN1F3PNLIP | |
| SCHEMBL15625215 | 0.69 | NR1H4 (0.35) | CES2CES1PTPN1F3PNLIP | |
| SCHEMBL15628369 | 0.69 | NR1H4 (0.35) | CES2CES1PTPN1F3PNLIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |