SCHEMBL29935

SCHEMBL29935

C=CCC(P)(CC=C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
ALDH1A1 P00352 3/20 0.52
HTT P42858 1/20 0.48
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAPT P10636 2/20 0.38
ATM Q13315 1/20 0.36
MAPK1 P28482 1/20 0.34
KCNN4 O15554 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1474121 0.79 ALDH1A1 (0.39) TSHRALDH1A1HTTKMT2AMAPT
SCHEMBL7740564 0.76 TSHR (0.55) TSHRALDH1A1HTTKMT2AMEN1
SCHEMBL5690296 0.76 TSHR (0.55) TSHRALDH1A1HTTKMT2AMEN1
SCHEMBL1862170 0.76 TSHR (0.55) TSHRALDH1A1HTTKMT2AMEN1
SCHEMBL601038 0.74 TSHR (0.53) TSHRALDH1A1HTTKMT2AMEN1
SCHEMBL30434815 0.74 HTT (0.55) TSHRALDH1A1HTTKMT2AMEN1
Ammonia Solution, Strong SCHEMBL11170544 0.74 TSHR (0.53) TSHRALDH1A1HTTKMT2AMEN1
SCHEMBL17940721 0.74 TSHR (0.48) TSHRALDH1A1HTTKMT2AMEN1
SCHEMBL2688608 0.73 HTT (0.53) TSHRALDH1A1HTTKMT2AMEN1
SCHEMBL1985443 0.73 ALDH1A1 (0.57) TSHRALDH1A1HTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 567 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240191112-A1 SOLVENTLESS ADHESIVE COMPOSITIONS AND LAMINATE MATERIALS PREPARED WITH THE SAME ARKEMA FRANCE (FR) 2024-06-13 US disclosed
EP-4377412-A1 SOLVENTLESS ADHESIVE COMPOSITIONS AND LAMINATE MATERIALS PREPARED WITH THE SAME Dow Global Technologies LLC (US) 2024-06-05 EP disclosed
EP-4377411-A1 SOLVENTLESS ADHESIVE COMPOSITIONS AND LAMINATE MATERIALS PREPARED THEREFROM Dow Global Technologies LLC (US) 2024-06-05 EP disclosed
EP-4377410-A1 SOLVENTLESS ADHESIVE COMPOSITIONS AND LAMINATE MATERIALS PREPARED WITH THE SAME Dow Global Technologies LLC (US) 2024-06-05 EP disclosed
CN-114641537-B Curable composition and method for bonding substrates 陶氏环球技术有限责任公司 2024-05-24 CN disclosed
CN-114667320-B Curable composition and application method thereof 陶氏环球技术有限责任公司 2024-05-24 CN disclosed
US-11981827-B2 Waterborne polyurethane dispersion and method for preparing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-14 US disclosed
WO-2024054480-A1 TERTIARY AMINE CATALYST FOR POLYURETHANE FOAM HUNTSMAN PETROCHEMICAL LLC (US) 2024-03-14 WO disclosed
US-20240067845-A1 Waterborne Coating Composition ARKEMA FRANCE (FR) 2024-02-29 US disclosed
US-20240052126-A1 Systems and Methods for Image-Based Location Determination SENSEN NETWORKS GROUP PTY LTD (AU) 2024-02-15 US disclosed
US-4208314-A LOW DENSITY POLYURETHANE FOAMS FROM POLYOLS WITH ADDITION POLYMER PARTICLES CONTAINED THEREIN UNION CARBIDE CORPORATION (US) 1980-06-17 US disclosed
EP-0010931-A1 Process for preparing polyurethane compositions emitting reduced amounts of toxic fumes on burning MOONEY CHEMICALS, INC. (US) 1980-05-14 EP disclosed
US-4172825-A Polymer/polyols and process for production thereof UNION CARBIDE CORPORATION (US) 1979-10-30 US disclosed
US-4162353-A HALOPHOSPHATES OR POLYMERS THEREOF UNION CARBIDE CORPORATION (US) 1979-07-24 US disclosed
US-4148840-A Polymer/polyol compositions made from preformed polymer/polyols, processes for making same and processes for making polyurethane products therefrom UNION CARBIDE CORPORATION (US) 1979-04-10 US disclosed
US-4143002-A CHALK-RESISTANT, MEDIUM TO DARK COLORED POLYURETHANES, POLYMER/POLYOL AND POLYISOCYANATE COMPOSITIONS FOR USE IN PRODUCING SAME AND METHODS FOR MAKING SAID POLYURETHANES UNION CARBIDE CORPORATION (US) 1979-03-06 US disclosed
US-4125505-A Polymer/polyols from high ethylene oxide content polyols UNION CARBIDE CORPORATION (US) 1978-11-14 US disclosed
US-4119586-A Polymer/polyol compositions, processes for making same and processes for making polyurethane products therefrom UNION CARBIDE CORPORATION (US) 1978-10-10 US disclosed
US-4110415-A FIRE RETARDANTS FOR POLYURETHANES, IMPROVE FLEXIBILITY TO PHENOLIC RESINS UNION CARBIDE CORPORATION (US) 1978-08-29 US disclosed
US-4097559-A TRIS(2-CHLORO-ETHYL)PHOSPHATE, TRIETHYL PHOSPHATE UNION CARBIDE CORPORATION (US) 1978-06-27 US disclosed