Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938315 | 0.86 | ALDH1A1 (0.46) | TSHRALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL7740564 | 0.78 | TSHR (0.55) | TSHRALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL5690296 | 0.78 | TSHR (0.55) | TSHRALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL1862170 | 0.78 | TSHR (0.55) | TSHRALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL30434815 | 0.76 | HTT (0.55) | TSHRALDH1A1HTTKMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL11170544 | 0.76 | TSHR (0.53) | TSHRALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL1501852 | 0.74 | TAAR1 (0.52) | TSHRALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL1985443 | 0.74 | ALDH1A1 (0.57) | TSHRALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL15644141 | 0.74 | TSHR (0.52) | TSHRALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL2688608 | 0.74 | HTT (0.53) | TSHRALDH1A1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040904-A1 | Boronate Medicaments for Preventing Thrombosis During Surgery | Trigen Holdings AG (GB) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040904-A1 | Boronate Medicaments for Preventing Thrombosis During Surgery | F9, FGB, TFPI | TSHR 282/4885ALDH1A1 3387/4885HTT 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.