Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PNLIP | P16233 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290270 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPK1PTGS2PNLIP | |
| SCHEMBL290271 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPK1PTGS2PNLIP | |
| SCHEMBL601710 | 0.92 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPK1PTGS2CES2 | |
| SCHEMBL4743756 | 0.89 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPK1PTGS2RAB9A | |
| SCHEMBL17417889 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1RAB9AMAPT | |
| SCHEMBL12832075 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPK1PTGS2PNLIP | |
| SCHEMBL10067446 | 0.82 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPK1PTGS2CES2 | |
| SCHEMBL6344467 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1PTGS2CES2 | |
| SCHEMBL13236533 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1PTGS2CES2 | |
| SCHEMBL6344463 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1PTGS2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427181-A2 | TOPICAL COMPOSITIONS COMPRISING AN ALKOXYLATED DIPHENYLACRYLATE COMPOUND AND AN ARYL CARBOXYLIC ESTER | ELC Management LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129321-A3 | TOPICAL COMPOSITIONS COMPRISING AN ALKOXYLATED DIPHENYLACRYLATE COMPOUND AND AN ARYL CARBOXYLIC ESTER | ELC MANAGEMENT LLC (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2010129321-A2 | TOPICAL COMPOSITIONS COMPRISING AN ALKOXYLATED DIPHENYLACRYLATE COMPOUND AND AN ARYL CARBOXYLIC ESTER | ELC MANAGEMENT LLC (US) | 2010-11-11 | — | — | WO | disclosed |