SCHEMBL6344463

SCHEMBL6344463

CCCCCCCCOC(=O)/C(C#N)=C(\c1ccccc1)c1ccc(OC)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
LMNA P02545 3/20 0.56
MAPK1 P28482 1/20 0.56
PTGS2 P35354 1/20 0.44
TSHR P16473 2/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
PLA2G4B P0C869 1/20 0.43
CYP19A1 P11511 1/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
RARB P10826 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13236533 1.00 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1PTGS2TSHR
SCHEMBL6344467 1.00 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1PTGS2TSHR
SCHEMBL14877495 0.92 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL1123572 0.92 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL7205837 0.92 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL5331475 0.92 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL5145142 0.91 LMNA (0.66) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL502564 0.89 LMNA (0.67) ALDH1A1LMNAMAPK1PTGS2TSHR
SCHEMBL12919793 0.89 MAPT (0.57) ALDH1A1LMNAMAPK1TSHRMAPT
SCHEMBL13236532 0.88 ALDH1A1 (0.49) ALDH1A1LMNAMAPK1PTGS2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6905525-B2 Candle wax stabilized with piperazinones CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-06-14 US disclosed
EP-1252227-B1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SC HOLDING AG (CH) 2004-09-22 EP disclosed
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP disclosed
US-6562084-B2 Against discoloration and fading; also a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US disclosed
US-6547840-B2 White, dyed, dipped, unscented and/or scented candle wax is effectively stabilized against discoloration and fading by the incorporation of an imidazolidine in combination with a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-15 US disclosed
US-6544305-B2 White, dyed, dipped, unscented and/or scented candle wax is effectively stabilized against discoloration and fading by the incorporation of an imidazolidine in combination with a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-08 US disclosed
US-6544304-B2 White, dyed, dipped, unscented and/or scented candle wax stabilized against discoloration/fading by a morpholinone, e.g., 2,3,3,4,5,5-hexamethylmorpholin-2-one; including an ultra-violet absorber; oxidation resistance CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-08 US disclosed
US-6540795-B2 Stabilized against discoloration and fading CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-01 US disclosed
US-20030051392-A1 CANDLE WAX STABILIZED WITH PIPERAZINDIONES CIBA SPECIALTY CHEMICALS CORP. 2003-03-20 US disclosed
US-20030005621-A1 Candle wax stabilized with morpholinones CIBA SPECIALTY CHEMICALS CORP. 2003-01-09 US disclosed
US-20030000128-A1 Candle wax stabilized with oxazolidines CIBA SPECIALTY CHEMICALS CORP. 2003-01-02 US disclosed
US-20030000130-A1 Candle wax stabilized with piperazinones CIBA SPECIALITY CHEMICALS CORP. 2003-01-02 US disclosed
US-20020194776-A1 Candle wax stabilized with imidazolidines CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
US-20020194777-A1 Candle wax stabilized with piperazinones CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
EP-1252227-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE Ciba SC Holding AG (CH) 2002-10-30 EP disclosed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed
WO-2001057126-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO disclosed
US-6221115-B1 WHITE, DYED, DIPPED, UNSCENTED AND/OR SCENTED CANDLE WAX STABILIZED BY A ULTRAVILET RADIATION ABSORBER AND HINDERED AMINE STABILIZING AGENT CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-24 US disclosed