SCHEMBL29935564

SCHEMBL29935564

COC(CSc1cc(C)c2ccccc2n1)OC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.54
CYP2C9 P11712 1/20 0.54
MAPT P10636 7/20 0.53
KMT2A Q03164 5/20 0.53
ALDH1A1 P00352 4/20 0.52
LMNA P02545 3/20 0.52
TSHR P16473 1/20 0.51
MEN1 O00255 4/20 0.50
HTT P42858 3/20 0.50
GAA P10253 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
BLM P54132 1/20 0.50
ATM Q13315 1/20 0.50
PRNP P04156 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
HPGD P15428 3/20 0.49
TP53 P04637 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22534237 1.00 CYP2C19 (0.54) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL29935493 0.80 L3MBTL1 (0.42) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL22534233 0.80 L3MBTL1 (0.42) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL5027088 0.78 MAPT (0.63) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL22534371 0.76 PRNP (0.50) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL29935543 0.76 PRNP (0.50) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL9821782 0.75 CYP2C9 (0.70) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL7936194 0.74 MAPT (0.73) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL6892230 0.74 CYP2C9 (0.77) CYP2C19CYP2C9MAPTKMT2AALDH1A1
SCHEMBL5803966 0.74 CYP2C9 (0.60) CYP2C19CYP2C9MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111793025-B Method for modifying amino in molecule by oxazoline quaternary ammonium salt and application thereof 中国科学院上海药物研究所 2022-09-23 CN disclosed