Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | NSD2 | O96028 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL11064940 | 0.87 | CYP2C9 (0.71) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL9821782 | 0.86 | CYP2C9 (0.70) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL3862194 | 0.82 | HPGD (0.76) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL5803966 | 0.79 | CYP2C9 (0.60) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL3455097 | 0.77 | RXFP1 (0.64) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL5027088 | 0.77 | MAPT (0.63) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL7936194 | 0.77 | MAPT (0.73) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL12259180 | 0.76 | ALDH1A1 (0.85) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL7262273 | 0.75 | RXFP1 (0.58) | CYP2C9CYP2C19HPGDLMNAKMT2A | |
| SCHEMBL1613311 | 0.74 | PRNP (1.00) | HPGDLMNAKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |