Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461573 | 0.78 | SIGMAR1 (0.39) | SIGMAR1DRD2NEK2 | |
| SCHEMBL18353161 | 0.73 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL5389801 | 0.71 | CRBN (0.37) | SIGMAR1DRD2 | |
| SCHEMBL9373179 | 0.69 | LMNA (0.34) | SIGMAR1DRD2 | |
| SCHEMBL9373229 | 0.69 | SIGMAR1 (0.36) | SIGMAR1DRD2NEK2 | |
| SCHEMBL15088421 | 0.67 | SIGMAR1 (0.35) | SIGMAR1DRD2 | |
| SCHEMBL722997 | 0.67 | BACE1 (0.47) | SIGMAR1DRD2 | |
| SCHEMBL7294932 | 0.66 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL7290522 | 0.66 | SIGMAR1 (0.31) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1285606 | 0.66 | MAPK1 (0.49) | SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220290159-A1 | miRNAS FOR REDUCING VENTRICLE ENLARGEMENT | St. Jude Children's Research Hpspital, Inc. (US) | 2022-09-15 | — | — | US | disclosed |