Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 12/20 | 0.36 |
| ▸ | JUN | P05412 | 10/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 10/20 | 0.36 |
| ▸ | RELA | Q04206 | 10/20 | 0.36 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | ATF1 | P18846 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682867 | 0.81 | TRPA1 (0.41) | SYKNFKB1JUNNFKB2RELA | |
| SCHEMBL1674220 | 0.74 | SYK (0.39) | SYK | |
| SCHEMBL1674236 | 0.73 | SYK (0.39) | SYK | |
| SCHEMBL358306 | 0.73 | SYK (0.41) | SYK | |
| SCHEMBL29723136 | 0.70 | — | — | |
| SCHEMBL16152612 | 0.70 | — | — | |
| SCHEMBL359942 | 0.69 | SYK (0.39) | SYK | |
| SCHEMBL367112 | 0.69 | SYK (0.41) | SYK | |
| SCHEMBL10254567 | 0.69 | ALDH1A1 (0.45) | SYK | |
| SCHEMBL29963047 | 0.69 | SYK (0.41) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073073-A1 | THIENOPYRIMIDINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2022-10-19 | — | — | EP | disclosed |