Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 5/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21522470 | 0.81 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL31464957 | 0.81 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL27424684 | 0.81 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL27424943 | 0.81 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23232002 | 0.80 | CHRM1 (0.51) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL12539812 | 0.79 | CHRM1 (0.52) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23215018 | 0.77 | CHRM1 (0.55) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23231394 | 0.77 | CHRM1 (0.55) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23292267 | 0.76 | CYP3A4 (0.55) | HRH2HRH1HRH3HSD11B1 | |
| SCHEMBL23215090 | 0.75 | CHRM1 (0.61) | CHRM1CHRM2CHRM4CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4322951-A1 | CRYSTALLINE COMPOUND OF MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | Pipeline Therapeutics, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022221450-A1 | CRYSTALLINE COMPOUND OF MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | Pipeline Therapeutics, Inc. (US) | 2022-10-20 | — | — | WO | disclosed |