Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.55 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.55 |
| ▸ | CCNK | O75909 | 3/20 | 0.52 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.52 |
| ▸ | CCR6 | P51684 | 7/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1036089 | 0.88 | CYP3A4 (0.53) | CYP3A4CYP2D6CYP2C9HSD11B1HSD11B2 | |
| SCHEMBL1036091 | 0.88 | CYP3A4 (0.53) | CYP3A4CYP2D6CYP2C9HSD11B1HSD11B2 | |
| SCHEMBL23292286 | 0.88 | CCNK (0.50) | CYP3A4CYP2D6CYP2C9HSD11B1HSD11B2 | |
| SCHEMBL23292322 | 0.86 | NOS2 (0.52) | CCNKCDK12CCR6NOS2NOS3 | |
| SCHEMBL23292432 | 0.84 | CCNK (0.51) | CYP3A4CYP2D6CYP2C9HSD11B1HSD11B2 | |
| SCHEMBL1036416 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2D6CYP2C9HSD11B1HSD11B2 | |
| SCHEMBL1036415 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2D6CYP2C9HSD11B1HSD11B2 | |
| SCHEMBL23292365 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2D6CYP2C9HSD11B1HSD11B2 | |
| SCHEMBL2636995 | 0.81 | HRH2 (0.41) | CYP3A4CYP2D6CYP2C9HSD11B1HSD11B2 | |
| SCHEMBL30088942 | 0.80 | HRH1 (0.48) | HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3813819-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Kinnate Biopharma Inc. (US) | 2021-05-05 | — | — | EP | disclosed |