Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30818415 | 0.96 | OPRM1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3203760 | 0.90 | KDM1A (0.45) | — | |
| SCHEMBL3203779 | 0.90 | KDM1A (0.45) | — | |
| SCHEMBL31665963 | 0.90 | REN (0.53) | OPRM1OPRD1 | |
| SCHEMBL29591954 | 0.87 | SLC6A2 (0.57) | OPRM1OPRD1 | |
| SCHEMBL30383148 | 0.85 | OPRM1 (0.53) | OPRM1OPRD1 | |
| SCHEMBL17722501 | 0.84 | OPRM1 (0.47) | OPRM1OPRD1 | |
| SCHEMBL31373856 | 0.84 | F2 (0.56) | OPRM1OPRD1 | |
| SCHEMBL30254020 | 0.82 | OPRM1 (0.43) | OPRM1OPRD1OPRK1 | |
| SCHEMBL31328325 | 0.82 | OPRM1 (0.43) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340633-A1 | SUPERAGONIST POLYPEPTIDE ANALOGS OF ADRENOMEDULLIN AND INTERMEDIN PEPTIDE HORMONES | ADEPTHERA LLC | 2022-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220340633-A1 | SUPERAGONIST POLYPEPTIDE ANALOGS OF ADRENOMEDULLIN AND INTERMEDIN PEPTIDE HORMONES | RAMP1, CALCRL, RAMP3 | OPRM1 186/4885OPRD1 683/4885OPRK1 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.