Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | RXFP3 | Q9NSD7 | 8/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12741617 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HTTSMN1; SMN2RXFP3L3MBTL1 | |
| SCHEMBL27412659 | 0.88 | ALDH1A1 (0.79) | ALDH1A1HTTSMN1; SMN2RXFP3MAPT | |
| SCHEMBL30633831 | 0.88 | ALDH1A1 (0.79) | ALDH1A1HTTSMN1; SMN2RXFP3MAPT | |
| SCHEMBL1902358 | 0.84 | SMN1; SMN2 (0.76) | ALDH1A1HTTSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL7462557 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HTTSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL19304098 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HTTSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL20676018 | 0.81 | SMN1; SMN2 (0.85) | ALDH1A1HTTSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL26660446 | 0.81 | SMN1; SMN2 (0.70) | ALDH1A1HTTSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL26791211 | 0.80 | ALDH1A1 (0.66) | ALDH1A1HTTRXFP3HPGDMAPT | |
| SCHEMBL9845474 | 0.79 | HPGD (0.74) | ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304630-A1 | SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM | Research Triangle Institute (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-116963761-A | Small molecule antagonists against relaxin-3/RXFP 3 system | 研究三角协会 | 2023-10-27 | — | — | CN | disclosed |
| WO-2022192126-A1 | SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM | RESEARCH TRIANGLE INSTITUTE (US) | 2022-09-15 | — | — | WO | disclosed |