Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449037 | 1.00 | F2 (0.53) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL841784 | 0.84 | ALDH1A1 (0.55) | CA1CA2POLBALDH1A1KMT2A | |
| SCHEMBL2786905 | 0.84 | GAA (0.51) | F2PRSS1PRSS2PRSS3MAPT | |
| SCHEMBL1421819 | 0.84 | P2RX1 (0.45) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7649266 | 0.84 | F2 (0.54) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL13430824 | 0.82 | F2 (0.53) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL18513400 | 0.81 | LCK (0.52) | CA1CA2MAPTUSP2POLB | |
| SCHEMBL732949 | 0.81 | LCK (0.57) | CA1CA2MAPTUSP2POLB | |
| SCHEMBL8519013 | 0.80 | ALDH1A1 (0.57) | CA1CA2POLBALDH1A1KMT2A | |
| SCHEMBL28667831 | 0.80 | POLB (0.51) | CA1CA2POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |
| EP-3931194-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-12-06 | — | — | EP | disclosed |
| EP-4087841-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2022-11-16 | — | — | EP | disclosed |
| CN-115023426-A | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达农作物保护股份公司 | 2022-09-06 | — | — | CN | disclosed |