SCHEMBL29938115

SCHEMBL29938115

CN1C(=O)CC[C@@H]1C(=O)Nc1cc(O[C@H]2CC[C@@H](C(F)(F)F)CC2)cc2c1OCC2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 19/20 0.36
SCN9A Q15858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24751497 1.00 P2RX7 (0.36) P2RX7SCN9A
SCHEMBL29938793 1.00 P2RX7 (0.36) P2RX7SCN9A
SCHEMBL29149215 1.00 P2RX7 (0.36) P2RX7SCN9A
SCHEMBL29937835 1.00 P2RX7 (0.36) P2RX7SCN9A
SCHEMBL29938327 1.00 P2RX7 (0.36) P2RX7SCN9A
SCHEMBL29149425 0.82 P2RX7 (0.45) P2RX7
SCHEMBL24750261 0.81 LMNA (0.42) P2RX7
SCHEMBL29149178 0.81 LMNA (0.42) P2RX7
SCHEMBL24750263 0.81 LMNA (0.42) P2RX7
SCHEMBL29938386 0.81 LMNA (0.42) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4323338-B1 TEAD INHIBITORS ORION CORP (FI) 2025-10-08 EP disclosed
EP-4323338-A1 TEAD INHIBITORS Orion Corporation (FI) 2024-02-21 EP disclosed
CN-117500786-A TEAD inhibitors 奥赖恩公司 2024-02-02 CN disclosed
WO-2022219246-A1 TEAD INHIBITORS ORION CORPORATION (FI) 2022-10-20 WO disclosed