SCHEMBL29938398

SCHEMBL29938398

Nc1ccc(N)c(-c2ccc(C=O)cc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 4/20 0.38
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD5 P21918 1/20 0.37
DRD3 P35462 1/20 0.37
PTGS1 P23219 1/20 0.37
CYP2A6 P11509 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH5A1 P51649 1/20 0.35
ABAT P80404 1/20 0.35
KIF11 P52732 1/20 0.35
RELA Q04206 1/20 0.34
TDP1 Q9NUW8 4/20 0.34
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 2/20 0.34
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6030003 1.00 DRD1 (0.38) DRD1DRD2DRD4DRD5DRD3
SCHEMBL28902120 0.85 ALDH1A1 (0.38) DRD1DRD2DRD4DRD5DRD3
SCHEMBL29418199 0.82 ALDH1A1 (0.42) DRD1DRD2DRD4DRD5DRD3
SCHEMBL12459069 0.81 PLA2G7 (0.42) DRD1DRD2DRD4DRD5DRD3
SCHEMBL12458455 0.81 ALDH1A1 (0.47) DRD1DRD2DRD4DRD5DRD3
SCHEMBL2479814 0.81 TDP1 (0.50) HSD17B10TDP1ALDH1A1CYP3A4NPC1
SCHEMBL30075769 0.81 TDP1 (0.50) HSD17B10TDP1ALDH1A1CYP3A4NPC1
SCHEMBL6571378 0.81 ALDH1A1 (0.42) HSD17B10RELATDP1ALDH1A1CYP3A4
SCHEMBL6574474 0.80 CA12 (0.45) CYP2A6TDP1ALDH1A1CYP3A4NPC1
Hydrochloric Acid SCHEMBL6571929 0.79 TDP1 (0.48) HSD17B10TDP1ALDH1A1CYP3A4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022191865-A1 HAIR COLORANT ASSESSMENT, SELECTION AND FORMULATION SYSTEM Innovative Beauty LLC (US) 2022-09-15 WO disclosed