Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675909 | 0.82 | VNN1 (0.46) | VNN1PDK1PDK2PDK3PDK4 | |
| SCHEMBL20738675 | 0.82 | EPHX2 (0.43) | KDM4DAAK1MEN1MAPTKMT2A | |
| SCHEMBL6163358 | 0.81 | CNR2 (0.51) | VNN1PDK1PDK2PDK3PDK4 | |
| SCHEMBL29717737 | 0.80 | GAA (0.43) | GAAMEN1ALDH1A1KMT2ARXFP1 | |
| SCHEMBL17018582 | 0.80 | CYP2C19 (0.44) | GAAAAK1MEN1MAPTKMT2A | |
| SCHEMBL21580080 | 0.80 | GAA (0.43) | GAAMEN1ALDH1A1KMT2ARXFP1 | |
| SCHEMBL5969759 | 0.78 | HDAC3 (0.46) | GAAAAK1ALDH1A1CTSSCTSK | |
| SCHEMBL3200118 | 0.78 | GAA (0.42) | GAAMEN1ALDH1A1KMT2ARXFP1 | |
| SCHEMBL2580865 | 0.78 | AAK1 (0.45) | GAAAAK1MEN1ALDH1A1KMT2A | |
| SCHEMBL31237071 | 0.78 | CNR2 (0.49) | VNN1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326257-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| US-20220348568-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | INC., CHEMOCENTRYX | 2022-11-03 | — | — | US | disclosed |
| WO-2022225832-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220348568-A1 | AZETIDINYL-ACETAMIDES AS CXCR7 INHIBITORS | CXCR1, CXCR5, CXCR6 | VNN1 3611/4885PDK1 1845/4885PDK2 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.