SCHEMBL2993887

SCHEMBL2993887

NC(=O)NCCC[C@H](NO)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
C3AR1 Q16581 1/20 0.51
SHMT1 P34896 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.41
OTC P00480 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KLK7 P49862 1/20 0.38
NOD1 Q9Y239 2/20 0.38
GNPAT O15228 1/20 0.38
FOLH1 Q04609 5/20 0.37
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
DDAH1 O94760 1/20 0.35
EPHX2 P34913 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
ITGB1 P05556 1/20 0.34
ITGA5 P08648 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27743728 1.00 C3AR1 (0.51) C3AR1SHMT1CTDSP1OTCMEN1
SCHEMBL25342849 0.94 C3AR1 (0.47) C3AR1SHMT1CTDSP1OTCMEN1
SCHEMBL29919408 0.87 C3AR1 (0.48) C3AR1SHMT1CTDSP1OTCMEN1
SCHEMBL8164682 0.85 C3AR1 (0.40) C3AR1OTCMEN1KMT2ANOD1
SCHEMBL117141 0.85 C3AR1 (0.40) C3AR1OTCMEN1KMT2ANOD1
SCHEMBL466294 0.85 C3AR1 (0.40) C3AR1OTCMEN1KMT2ANOD1
SCHEMBL5497855 0.85 C3AR1 (0.55) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL29429369 0.85 GNPAT (0.49) C3AR1SHMT1CTDSP1OTCMEN1
SCHEMBL5497852 0.85 C3AR1 (0.55) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL93363 0.83 C3AR1 (0.47) C3AR1SHMT1CTDSP1OTCMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100247463-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2010-09-30 US disclosed
US-7776844-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2010-08-17 US disclosed
US-20090208499-A1 N-(Phosphonoalkyl)-Amino Acids, Derivatives Thereof and Compositions and Methods of Use YU RUEY J 2009-08-20 US disclosed
US-7572776-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2009-08-11 US disclosed
US-20080306025-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2008-12-11 US disclosed
US-7429575-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2008-09-30 US disclosed
US-20070161543-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2007-07-12 US disclosed
WO-2005102043-A2 USE OF NICKEL TO CORRECT GROWTH DISORDERS IN PLANTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-11-03 WO disclosed
US-20050245397-A1 Use of nickel to correct growth disorders in plants NIPAN, LLC 2005-11-03 US disclosed