Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499265 | 0.83 | F12 (0.41) | NPSR1RXFP1BTKSMOPARP1 | |
| SCHEMBL29725995 | 0.82 | NPSR1 (0.46) | NPSR1RXFP1PARP1ALDH1A1IRAK4 | |
| SCHEMBL2078208 | 0.74 | IKBKB (0.41) | PARP1KDM4EALDH1A1HPGDMAP3K5 | |
| SCHEMBL30062375 | 0.73 | MAPT (0.42) | L3MBTL1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| Formic Acid SCHEMBL31708378 | 0.72 | TGFBR1 (0.35) | MAP4K4EGFRFRKMAPK9CSNK1D | |
| SCHEMBL15048600 | 0.72 | KLK3 (0.47) | L3MBTL1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL20086025 | 0.71 | IRAK4 (0.53) | MAP4K4EGFRFRKMAPK9CSNK1D | |
| SCHEMBL19207113 | 0.70 | JMJD6 (0.44) | L3MBTL1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11606947 | 0.70 | CHEK1 (0.41) | NPSR1BTKMAP4K4MAPK9L3MBTL1 | |
| SCHEMBL7520947 | 0.69 | PDE10A (0.42) | L3MBTL1PARP1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997681-B | Thiazolopyridine derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2022-11-15 | — | — | CN | disclosed |