Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3002348 | 0.89 | SLC16A3 (0.52) | MEN1HSP90AA1KMT2AMAOBALDH1A1 | |
| SCHEMBL630698 | 0.85 | MEN1 (0.57) | MEN1HSP90AA1KMT2AMAOBALDH1A1 | |
| SCHEMBL2805603 | 0.82 | ALDH1A1 (0.61) | MEN1HSP90AA1KMT2AMAOBALDH1A1 | |
| SCHEMBL2996551 | 0.82 | HDAC8 (0.52) | MEN1HSP90AA1KMT2AMAOBALDH1A1 | |
| SCHEMBL29376294 | 0.82 | HDAC8 (0.52) | MEN1HSP90AA1KMT2AMAOBALDH1A1 | |
| SCHEMBL629817 | 0.81 | MEN1 (0.46) | MEN1HSP90AA1KMT2AMAOBALOX5 | |
| SCHEMBL11336367 | 0.81 | L3MBTL1 (0.58) | MEN1HSP90AA1KMT2AMAOBALDH1A1 | |
| SCHEMBL13278206 | 0.80 | ALDH1A1 (0.55) | MEN1HSP90AA1KMT2AMAOBALDH1A1 | |
| SCHEMBL3003345 | 0.79 | ALDH1A1 (0.47) | KMT2AMAOBALDH1A1L3MBTL1TSHR | |
| SCHEMBL629641 | 0.79 | SLC16A3 (0.62) | MEN1HSP90AA1KMT2AMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197744-A1 | Organic Compounds | BARNES DAVID | 2010-08-05 | — | — | US | disclosed |
| EP-2155704-A1 | THIADIAZOLE DERIVATIVES AS ANTIDIABETIC AGENTS | Novartis Ag (CH) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008148744-A1 | THIADIAZOLE DERIVATIVES AS ANTIDIABETIC AGENTS | NOVARTIS AG (CH) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197744-A1 | Organic Compounds | PTPRS, PTPRO, PTPRC | MEN1 4409/4885HSP90AA1 2633/4885KMT2A 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.