SCHEMBL29940592

SCHEMBL29940592

CCCn1cc(C#N)c2cc(NC(=O)c3ccnc(Cl)c3)ccc21

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
XDH P47989 16/20 0.61
CA9 Q16790 3/20 0.59
CA12 O43570 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28429924 1.00 XDH (0.61) XDHCA9CA12
SCHEMBL29940470 0.92 CA9 (0.69) XDHCA9CA12
SCHEMBL28429359 0.92 CA9 (0.69) XDHCA9CA12
SCHEMBL29940871 0.89 XDH (0.61) XDHCA9CA12
SCHEMBL28429980 0.89 XDH (0.61) XDHCA9CA12
SCHEMBL28896300 0.87 CA9 (0.67) XDHCA9CA12
SCHEMBL29940813 0.87 CA9 (0.67) XDHCA9CA12
SCHEMBL28429322 0.87 XDH (0.72) XDHCA9
SCHEMBL29940711 0.87 XDH (0.65) XDHCA9CA12
SCHEMBL29940471 0.87 XDH (0.65) XDHCA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111072634-B 1-substituted-3-substituted-5-substituted amide-1H-indole compound and preparation method and application thereof 中国医科大学 2022-07-22 CN disclosed