Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | IL1RN | P18510 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048441 | 0.83 | ALDH1A1 (0.63) | GAALMNASMN1; SMN2TSHRHTT | |
| SCHEMBL3000302 | 0.83 | USP2 (0.59) | LMNASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL1002282 | 0.82 | ALDH1A1 (0.61) | GAALMNASMN1; SMN2TSHRHTT | |
| Hydrochloric Acid SCHEMBL5476884 | 0.81 | ALDH1A1 (0.59) | GAALMNASMN1; SMN2TSHRHTT | |
| SCHEMBL12327773 | 0.80 | ALDH1A1 (0.63) | GAALMNASMN1; SMN2TSHRHTT | |
| SCHEMBL370058 | 0.79 | SMN1; SMN2 (0.56) | GAALMNASMN1; SMN2TSHRHTT | |
| SCHEMBL256083 | 0.79 | ALDH1A1 (0.63) | GAALMNASMN1; SMN2TSHRHTT | |
| SCHEMBL1001472 | 0.79 | ALDH1A1 (0.62) | GAALMNASMN1; SMN2TSHRHTT | |
| SCHEMBL31728120 | 0.79 | ALDH1A1 (0.61) | GAALMNASMN1; SMN2TSHRHTT | |
| SCHEMBL5039031 | 0.79 | GAA (0.97) | GAALMNASMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | SIGA TECHNOLOGIES, INC. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | EIF2AK2, HAVCR2, SNRPE | GAA 97/4885LMNA 3407/4885SMN1; SMN2 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.