Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | IL1RN | P18510 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048441 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL12327773 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL2994061 | 0.79 | GAA (0.63) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL256083 | 0.79 | ALDH1A1 (0.63) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL1002282 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL31728120 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL6364945 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL28004350 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL16963746 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2LMNATSHRHTTMAPT | |
| SCHEMBL5738424 | 0.76 | TSHR (0.50) | SMN1; SMN2LMNATSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009137-A1 | CRTH2 MODULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | disclosed |