Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095691 | 0.73 | KDM1A (0.46) | KDM1AMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL17311800 | 0.73 | EPHX2 (0.50) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL12670826 | 0.72 | HTR2C (0.45) | MAOAMEN1KMT2ATDP1GAA | |
| SCHEMBL12196007 | 0.72 | NFKB1 (0.46) | TSHRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL12782076 | 0.72 | NFKB1 (0.46) | TSHRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL8926256 | 0.70 | GRIN2B (0.49) | GRIN2BKDM1AMAOABCHEACHE | |
| SCHEMBL27797781 | 0.69 | GRIN2B (0.56) | GRIN2BKDM1AMAOABCHEACHE | |
| SCHEMBL21119443 | 0.69 | HTR2C (0.42) | MAOAFUCA1MEN1KMT2ATDP1 | |
| SCHEMBL15506392 | 0.68 | MAPT (0.35) | GRIN2BKDM1AMAOAFUCA1TSHR | |
| SCHEMBL12514578 | 0.68 | SIGMAR1 (0.42) | GRIN2BKDM1AMAOATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109006-A | 3-substituted-1, 2-benzoxazine-4-ketone compound and preparation method thereof | 上海大学 | 2022-09-27 | — | — | CN | disclosed |