Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 12/20 | 0.61 |
| ▸ | HTR2B | P41595 | 3/20 | 0.61 |
| ▸ | HTR5A | P47898 | 3/20 | 0.61 |
| ▸ | IDO1 | P14902 | 4/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817460 | 0.82 | TDO2 (0.80) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL12938247 | 0.80 | TDO2 (0.67) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL23098942 | 0.80 | HTR2B (0.61) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL29693816 | 0.80 | HTR2B (0.61) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL28066961 | 0.79 | TDO2 (0.70) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL28811802 | 0.78 | BCHE (0.69) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL29891581 | 0.77 | HTR2B (0.65) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL24105915 | 0.76 | TDO2 (1.00) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL30431392 | 0.76 | TDO2 (1.00) | TDO2HTR2BHTR5AIDO1BCHE | |
| SCHEMBL1798020 | 0.76 | TDO2 (0.64) | TDO2HTR2BHTR5AIDO1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150150770-A1 | METHODS OF TREATING SKIN | TRACIE MARTYN INTERNATIONAL INC (US) | 2015-06-04 | — | — | US | disclosed |
| US-20140155961-A1 | METHODS OF TREATING SKIN | Tracie Martyn International, Inc. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20100272790-A1 | Methods of Treating Skin | TRACIE MARTYN INTERNATIONAL, LLC (US) | 2010-10-28 | — | — | US | disclosed |
| US-7776915-B2 | Topical formulations and methods of use | TRACIE MARTYN INTERNATIONAL, LLC (US) | 2010-08-17 | — | — | US | disclosed |
| EP-1360186-B1 | CARBOLINE DERIVATIVES | LILLY ICOS LLC (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20060216251-A1 | Topical formulations and methods of use | TRACIE MARTYN INTERNATIONAL, LLC (US) | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155961-A1 | METHODS OF TREATING SKIN | CUTA, LIPA, DLAT | TDO2 2587/4885HTR2B 3442/4885HTR5A 2786/4885 |
| US-20100272790-A1 | Methods of Treating Skin | CUTA, LIPA, DLAT | TDO2 2587/4885HTR2B 3442/4885HTR5A 2786/4885 |
| US-20150150770-A1 | METHODS OF TREATING SKIN | CUTA, LIPA, DLAT | TDO2 2587/4885HTR2B 3442/4885HTR5A 2786/4885 |
| US-20060216251-A1 | Topical formulations and methods of use | CPT1B, SLC25A20, CPT1A | TDO2 2305/4885HTR2B 2961/4885HTR5A 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.