SCHEMBL30009833

SCHEMBL30009833

CCc1cc2c(cc1C1CCN(C(=O)O)CC1)C(C)(C)c1[nH]c3cc(Br)ccc3c1C2

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 19/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009789 0.90 ALK (0.40) ALK
SCHEMBL29940669 0.89 ALK (0.48) ALK
SCHEMBL27087527 0.89 ALK (0.48) ALK
SCHEMBL27087525 0.88 ALK (0.41) ALK
SCHEMBL27087547 0.86 ALK (0.36) ALK
SCHEMBL30760744 0.84 ALK (0.54) ALK
SCHEMBL30010134 0.77 ALK (0.42) ALK
SCHEMBL30009523 0.76 ALK (0.55) ALK
SCHEMBL27087617 0.76 ALK (0.38) ALK
SCHEMBL30009875 0.75 ALK (0.53) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022237813-A1 COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF 盛世泰科生物医药技术(苏州)有限公司 2022-11-17 WO disclosed