SCHEMBL2994067

SCHEMBL2994067

O=C(O)c1ccc(C(=O)/C=C/c2cccc(C(=O)O)c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 5/20 0.74
MAOB P27338 4/20 0.65
MAPT P10636 3/20 0.65
CYP1B1 Q16678 3/20 0.65
BCHE P06276 2/20 0.65
PLIN1 O60240 1/20 0.65
LMNA P02545 1/20 0.65
TNFRSF1A P19438 1/20 0.65
ACHE P22303 1/20 0.65
RECQL P46063 1/20 0.65
PLIN5 Q00G26 1/20 0.65
ABHD5 Q8WTS1 1/20 0.65
HDAC3 O15379 1/20 0.60
HDAC4 P56524 1/20 0.60
HDAC1 Q13547 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC2 Q92769 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC8 Q9BY41 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2994069 1.00 P4HB (0.74) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL30384014 1.00 P4HB (0.74) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL7338947 0.95 P4HB (0.77) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL31233485 0.95 P4HB (0.77) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL7338954 0.95 P4HB (0.77) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL11452322 0.92 P4HB (0.78) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL30383950 0.92 P4HB (0.78) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL11452324 0.92 P4HB (0.78) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL2993136 0.91 P4HB (0.82) P4HBMAOBMAPTCYP1B1BCHE
SCHEMBL2993138 0.91 P4HB (0.82) P4HBMAOBMAPTCYP1B1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-7787085-B2 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2010-08-31 US disclosed
US-20080123046-A1 OPTICAL ALIGNMENT METHOD AND LIQUID CRYSTAL DISPLAY ELEMENT JSR CORPORATION (JP) 2008-05-29 US disclosed
US-20050259203-A1 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2005-11-24 US disclosed
EP-1353217-A1 Optical alignment method and liquid crystal display element JSR Corporation (JP) 2003-10-15 EP disclosed
US-6224788-B1 AROMATIC UNSATURATED KETONE POLYMERS JSR CORPORATION (JP) 2001-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B P4HB 552/4885MAOB 1004/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885MAOB 2435/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885MAOB 2435/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.