SCHEMBL29940725

SCHEMBL29940725

Nc1c(-c2ccc3ccccc3c2)ccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.52
DHFR P00374 1/20 0.49
KDM4E B2RXH2 2/20 0.47
CYP1A2 P05177 1/20 0.46
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
PIM1 P11309 2/20 0.44
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP1A1 P04798 2/20 0.43
CYP1B1 Q16678 2/20 0.43
NPC1 O15118 1/20 0.43
AR P10275 1/20 0.43
MAPT P10636 1/20 0.43
NFKB1 P19838 1/20 0.43
RAB9A P51151 1/20 0.43
GFER P55789 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6308539 1.00 GSTP1 (0.52) GSTP1DHFRKDM4ECYP1A2ADORA2A
SCHEMBL29830364 0.84 HPRT1 (0.46) CYP1A2ALDH1A1HSD17B10CYP1A1CYP1B1
SCHEMBL3193310 0.83 GSTP1 (0.64) GSTP1DHFRKDM4ECYP1A2ADORA2A
SCHEMBL23443653 0.82 PRKCZ (0.53) KDM4EALDH1A1HSD17B10CYP3A4NPC1
SCHEMBL15271981 0.82 HSD17B10 (0.43) KDM4ECYP1A2ALDH1A1HSD17B10CYP3A4
SCHEMBL29798181 0.82 HSD17B10 (0.43) KDM4ECYP1A2ALDH1A1HSD17B10CYP3A4
SCHEMBL21068 0.82 ALDH1A1 (0.46) KDM4ECYP1A2ALDH1A1HSD17B10CYP3A4
SCHEMBL30574434 0.82 ALDH1A1 (0.46) KDM4ECYP1A2ALDH1A1HSD17B10CYP3A4
SCHEMBL29423352 0.82 ALDH1A1 (0.46) KDM4ECYP1A2ALDH1A1HSD17B10CYP3A4
SCHEMBL28258564 0.82 TSHR (0.44) GSTP1MAPTSMN1; SMN2HPRT1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117264200-A Synthetic method and application of ethylenedioxythiophene bridged organic polymer 天津理工大学 2023-12-22 CN claimed
CN-112778518-B Amide-bridged organic polymer hole transport material and synthesis method and application thereof 天津理工大学 2022-07-22 CN claimed
CN-111848415-B Compound, organic electronic light-emitting device containing compound and application of compound 北京鼎材科技有限公司 2024-04-05 CN disclosed
CN-112778518-B Amide-bridged organic polymer hole transport material and synthesis method and application thereof 天津理工大学 2022-07-22 CN disclosed