Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185262 | 0.90 | MAPT (0.51) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL9185269 | 0.90 | MAPT (0.51) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL3293089 | 0.84 | MAPT (0.49) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL3293086 | 0.84 | MAPT (0.49) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL17881680 | 0.79 | MAPT (0.48) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL1137907 | 0.78 | MEN1 (0.49) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL1070286 | 0.78 | MEN1 (0.53) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL14186862 | 0.78 | MAPT (0.53) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| Ethane SCHEMBL7072851 | 0.78 | MAPT (0.49) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL11814908 | 0.77 | MAPT (0.51) | MAPTKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072476-B | Method for high-selectivity fluoromethylation of beta-keto ester compounds on oxygen | 南京理工大学 | 2022-10-21 | — | — | CN | disclosed |