Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.62 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.62 |
| ▸ | CDK2 | P24941 | 3/20 | 0.62 |
| ▸ | CDK9 | P50750 | 3/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.62 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.62 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.60 |
| ▸ | FYN | P06241 | 8/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16331301 | 0.82 | MKNK1 (0.60) | DYRK1ADYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL4052810 | 0.82 | DYRK1A (0.65) | DYRK1ADYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL22189861 | 0.80 | MKNK1 (0.77) | DYRK1ADYRK3CCNA2CDK2CDK5 | |
| SCHEMBL6071200 | 0.80 | DYRK1A (0.49) | DYRK1ADYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL16332085 | 0.79 | EGLN2 (0.66) | DYRK1AMKNK1KLK7 | |
| SCHEMBL10145505 | 0.79 | DYRK1A (0.63) | DYRK1ADYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL29555808 | 0.78 | DYRK1A (0.67) | DYRK1ADYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL5946455 | 0.78 | DYRK3 (0.47) | DYRK1ADYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL13234217 | 0.77 | DYRK1A (1.00) | DYRK1ADYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL2943851 | 0.77 | DYRK1A (0.59) | DYRK1ADYRK3CCNT1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |