Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.65 |
| ▸ | DYRK3 | O43781 | 4/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.65 |
| ▸ | CDK9 | P50750 | 4/20 | 0.65 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.65 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.65 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.65 |
| ▸ | CDK2 | P24941 | 2/20 | 0.65 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.64 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.60 |
| ▸ | FYN | P06241 | 3/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16331591 | 0.83 | MKNK1 (0.71) | DYRK1ADYRK3CCNT1CDK9DYRK2 | |
| SCHEMBL16331301 | 0.82 | MKNK1 (0.60) | DYRK1ADYRK3CCNT1CDK9DYRK2 | |
| SCHEMBL29941012 | 0.82 | DYRK1A (0.62) | DYRK1ADYRK3CCNT1CDK9DYRK2 | |
| SCHEMBL22189861 | 0.80 | MKNK1 (0.77) | DYRK1ADYRK3DYRK2DYRK1BCDK5 | |
| SCHEMBL16332085 | 0.79 | EGLN2 (0.66) | DYRK1AEGLN2MKNK1PIM1KLK7 | |
| SCHEMBL102942 | 0.79 | DYRK1A (1.00) | DYRK1ADYRK3CCNT1CDK9DYRK2 | |
| SCHEMBL16332731 | 0.79 | MKNK1 (0.60) | DYRK1ADYRK3CCNT1CDK9DYRK2 | |
| SCHEMBL22189894 | 0.78 | EGLN2 (0.65) | DYRK1ADYRK3CCNT1CDK9DYRK2 | |
| SCHEMBL29555808 | 0.78 | DYRK1A (0.67) | DYRK1ADYRK3CCNT1CDK9DYRK2 | |
| SCHEMBL22189748 | 0.78 | MKNK1 (0.56) | DYRK1ADYRK3CCNT1CDK9DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240041868-A1 | Methods, Compositions, and Uses of Novel FYN Kinase Inhibitors | Pathways Neuro Pharma, Inc. | 2024-02-08 | — | — | US | disclosed |
| US-11701353-B2 | Methods, compositions, and uses of novel FYN kinase inhibitors | Pathways Neuro Pharma, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| EP-2044071-A1 | OOXO-SUBSTITUTED IMIDAZO[1,2b]PYRIDAZINES, PRODUCTION AND USE THEREOF AS DRUGS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007147646-A1 | OXO-SUBSTITUTED IMIDAZO[1,2b]PYRIDAZINES, PRODUCTION AND USE THEREOF AS DRUGS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240041868-A1 | Methods, Compositions, and Uses of Novel FYN Kinase Inhibitors | FYN, LCK, PTK2B | DYRK1A 228/4885DYRK3 265/4885CCNT1 4406/4885 |
| US-11701353-B2 | Methods, compositions, and uses of novel FYN kinase inhibitors | FYN, LCK, PTK2B | DYRK1A 228/4885DYRK3 265/4885CCNT1 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.