Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.66 |
| ▸ | EPHX1 | P07099 | 13/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10383489 | 0.81 | ALDH1A1 (0.50) | EPHX2EPHX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL14606844 | 0.81 | EPHX2 (0.81) | EPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL16060396 | 0.79 | EPHX2 (0.65) | EPHX2EPHX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL1065092 | 0.78 | EPHX2 (1.00) | EPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL24308699 | 0.78 | EPHX1 (1.00) | EPHX2EPHX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL12196101 | 0.78 | EPHX1 (1.00) | EPHX2EPHX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL23960132 | 0.78 | EPHX1 (1.00) | EPHX2EPHX1ALDH1A1KDM4ENPC1 | |
| 1,3-Dicyclohexylurea SCHEMBL2755 | 0.78 | EPHX1 (1.00) | EPHX2EPHX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL12196125 | 0.78 | EPHX1 (1.00) | EPHX2EPHX1ALDH1A1KDM4ENPC1 | |
| SCHEMBL24308701 | 0.78 | EPHX1 (1.00) | EPHX2EPHX1ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |