Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15617048 | 0.79 | DYRK1A (0.57) | ARDYRK1ANR4A2HTR2ASLC6A4 | |
| SCHEMBL28251367 | 0.77 | DYRK1A (0.60) | ARDYRK1ANR4A2HTR2ASLC6A4 | |
| SCHEMBL21067626 | 0.74 | NR4A2 (0.47) | ARDYRK1ANR4A2HTR2A | |
| SCHEMBL4078677 | 0.72 | DYRK1A (0.55) | ARDYRK1ANR4A2HTR2ASLC6A4 | |
| SCHEMBL19836839 | 0.72 | DYRK1A (0.55) | ARDYRK1ANR4A2HTR2ASLC6A4 | |
| SCHEMBL15617054 | 0.72 | DYRK1A (0.55) | ARDYRK1ANR4A2HTR2ASLC6A4 | |
| SCHEMBL25293100 | 0.72 | HTR2A (0.49) | ARDYRK1ANR4A2HTR2ASLC6A4 | |
| SCHEMBL30548044 | 0.72 | HTR2A (0.49) | ARDYRK1ANR4A2HTR2ASLC6A4 | |
| SCHEMBL2036977 | 0.72 | NR4A2 (0.69) | DYRK1ANR4A2HTR2A | |
| SCHEMBL31542356 | 0.72 | NR4A2 (0.69) | DYRK1ANR4A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |