Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | MAP2 | P11137 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542356 | 0.76 | NR4A2 (0.69) | NR4A2KDM4EDYRK1AHTR2AALDH1A1 | |
| SCHEMBL2036977 | 0.76 | NR4A2 (0.69) | NR4A2KDM4EDYRK1AHTR2AALDH1A1 | |
| Lycogalic Acid A SCHEMBL29465596 | 0.75 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDPBRM1 | |
| Lycogalic Acid A SCHEMBL12955978 | 0.75 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDPBRM1 | |
| SCHEMBL29941741 | 0.74 | AR (0.54) | NR4A2ARDYRK1AHTR2A | |
| SCHEMBL24896562 | 0.73 | MAP2 (0.78) | MAP2KDM4EDYRK1ARPA1MCL1 | |
| SCHEMBL15617048 | 0.73 | DYRK1A (0.57) | NR4A2MAP2ARDYRK1ACLK1 | |
| SCHEMBL24896367 | 0.71 | KDM4E (0.55) | MAP2KDM4EDYRK1ARPA1MCL1 | |
| SCHEMBL2979929 | 0.71 | CSNK2A2 (0.69) | NR4A2KDM4EDYRK1AALDH1A1HPGD | |
| SCHEMBL12658020 | 0.71 | F7 (0.60) | NR4A2MAP2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |