Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 7/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | STK3 | Q13188 | 1/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23389145 | 1.00 | DDR1 (0.47) | DDR1ROCK2MCHR1JAK2PRKD3 | |
| SCHEMBL23389143 | 1.00 | DDR1 (0.47) | DDR1ROCK2MCHR1JAK2PRKD3 | |
| SCHEMBL23389181 | 0.82 | KMT2A (0.51) | KDM4EGAAKMT2AHRH3MAPT | |
| SCHEMBL29943552 | 0.82 | KMT2A (0.51) | KDM4EGAAKMT2AHRH3MAPT | |
| SCHEMBL23389178 | 0.82 | KMT2A (0.51) | KDM4EGAAKMT2AHRH3MAPT | |
| SCHEMBL23389100 | 0.79 | ROCK2 (0.44) | DDR1ROCK2MCHR1JAK2PRKD3 | |
| SCHEMBL23389097 | 0.79 | ROCK2 (0.44) | DDR1ROCK2MCHR1JAK2PRKD3 | |
| SCHEMBL23389119 | 0.78 | ROCK2 (0.48) | DDR1ROCK2JAK2PRKD3PRKCG | |
| SCHEMBL23389118 | 0.78 | ROCK2 (0.48) | DDR1ROCK2JAK2PRKD3PRKCG | |
| SCHEMBL16528537 | 0.76 | DDR1 (0.54) | DDR1MCHR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061341-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | The Regents of the University of California (US) | 2022-09-28 | — | — | EP | disclosed |