Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23389181 | 1.00 | KMT2A (0.51) | KMT2AMEN1FPR2KDM4EGAA | |
| SCHEMBL23389178 | 1.00 | KMT2A (0.51) | KMT2AMEN1FPR2KDM4EGAA | |
| SCHEMBL23389233 | 0.85 | KMT2A (0.46) | KMT2AMEN1CA1CA2HRH3 | |
| SCHEMBL23389232 | 0.85 | KMT2A (0.46) | KMT2AMEN1CA1CA2HRH3 | |
| SCHEMBL29943544 | 0.82 | DDR1 (0.47) | KMT2AKDM4EGAACA1CA2 | |
| SCHEMBL23389143 | 0.82 | DDR1 (0.47) | KMT2AKDM4EGAACA1CA2 | |
| SCHEMBL23389145 | 0.82 | DDR1 (0.47) | KMT2AKDM4EGAACA1CA2 | |
| SCHEMBL23419189 | 0.81 | FPR2 (0.55) | KMT2AMEN1FPR2KDM4EGAA | |
| SCHEMBL21235453 | 0.80 | KMT2A (0.55) | KMT2AMEN1FPR2HRH3PARP1 | |
| SCHEMBL29991244 | 0.80 | KMT2A (0.55) | KMT2AMEN1FPR2HRH3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061341-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | The Regents of the University of California (US) | 2022-09-28 | — | — | EP | disclosed |