Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630384 | 1.00 | PRMT1 (0.39) | PRMT1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL29944222 | 0.84 | KDM4E (0.36) | HDAC3MAPTALDH1A1KDM4EGAA | |
| SCHEMBL23630386 | 0.84 | KDM4E (0.36) | HDAC3MAPTALDH1A1KDM4EGAA | |
| SCHEMBL64634 | 0.76 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC6MAPT | |
| SCHEMBL5227048 | 0.76 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC6MAPT | |
| SCHEMBL23630370 | 0.76 | OGA (0.49) | PRMT1MAPTLMNAALDH1A1GAA | |
| SCHEMBL23630486 | 0.76 | P2RY12 (0.53) | PRMT1P2RY12MAPTALDH1A1KDM4E | |
| SCHEMBL29944132 | 0.76 | P2RY12 (0.53) | PRMT1P2RY12MAPTALDH1A1KDM4E | |
| SCHEMBL63685 | 0.75 | KDM4E (0.47) | HDAC3HDAC4HDAC1HDAC6MAPT | |
| SCHEMBL26147989 | 0.75 | HSD11B1 (0.42) | PRMT1MAPTLMNAALDH1A1IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087658-A1 | SMARCA2-VHL DEGRADERS | Amgen Inc. (US) | 2022-11-16 | — | — | EP | disclosed |