Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.50 |
| ▸ | GSPT1 | P15170 | 3/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 11/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.45 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23357891 | 1.00 | CRBN (0.50) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL23357943 | 0.91 | CRBN (0.50) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL32689595 | 0.91 | CRBN (0.50) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL29944388 | 0.90 | CRBN (0.50) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL23357985 | 0.90 | CRBN (0.50) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL23358012 | 0.89 | CRBN (0.56) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL29944282 | 0.89 | CRBN (0.56) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL23358016 | 0.89 | CRBN (0.53) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL23357921 | 0.88 | CRBN (0.52) | CRBNGSPT1DDB1IKZF3CSNK1A1 | |
| SCHEMBL29944430 | 0.88 | CRBN (0.52) | CRBNGSPT1DDB1IKZF3CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061812-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | Bristol-Myers Squibb Company (US) | 2022-09-28 | — | — | EP | claimed |
| EP-4061812-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | Bristol-Myers Squibb Company (US) | 2022-09-28 | — | — | EP | disclosed |