SCHEMBL29944734

SCHEMBL29944734

C=CC(=O)Oc1cc(N)ccc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
KDM4E B2RXH2 9/20 0.47
MAPT P10636 6/20 0.47
CYP3A4 P08684 3/20 0.47
GAA P10253 3/20 0.47
ESR2 Q92731 2/20 0.47
PTPN1 P18031 1/20 0.47
HPGD P15428 4/20 0.44
HSD17B10 Q99714 4/20 0.44
TDP1 Q9NUW8 5/20 0.43
THRB P10828 4/20 0.43
MEN1 O00255 2/20 0.43
RECQL P46063 2/20 0.43
KMT2A Q03164 2/20 0.43
KDR P35968 2/20 0.43
USP2 O75604 2/20 0.43
CYP2C19 P33261 2/20 0.43
POLB P06746 2/20 0.43
BLM P54132 2/20 0.43
PTGS2 P35354 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1468631 1.00 ALDH1A1 (0.58) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL5267229 0.87 KDM4E (0.47) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL29716033 0.87 KDM4E (0.47) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL29083497 0.84 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL29217583 0.82 KDM4E (0.45) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL10533244 0.82 ESR1 (0.58) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL27766549 0.81 THRB (0.39) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL27494979 0.81 THRB (0.43) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL29258048 0.81 KDM4E (0.41) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL821894 0.81 KDM4E (0.45) ALDH1A1KDM4EMAPTGAAESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768146-A Adhesive composition for dental use 可乐丽则武齿科株式会社 2025-04-04 CN disclosed
CN-119587384-A Dental ceramic prosthesis and surface modification material thereof 嘉兴市京吟生物科技有限公司 2025-03-11 CN disclosed
EP-3682862-B1 CURABLE DENTAL COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-11-20 EP disclosed
CN-113402666-B Dental photocurable composition excellent in color tone selectivity 株式会社松风 2024-11-15 CN disclosed
CN-113402665-B Dental photocurable composition comprising a highly soluble photoacid generator 株式会社松风 2024-11-15 CN disclosed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
US-11767411-B2 Curable composition containing transition metal adsorbent SHOFU INC. (JP) 2023-09-26 US disclosed
US-11453761-B2 Composite material, curable composition, and method for producing curable composition TOKUYAMA DENTAL CORPORATION (JP) 2022-09-27 US disclosed
US-11452675-B2 Dental curable composition TOKUYAMA DENTAL CORPORATION (JP) 2022-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11452675-B2 Dental curable composition SP1, H1-0, ERH ALDH1A1 1047/4885KDM4E 3039/4885MAPT 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.