Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141692 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL7141330 | 0.84 | CYP2C9 (0.64) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Chromonar SCHEMBL309094 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Chromonar SCHEMBL29724124 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL1476174 | 0.82 | HSD17B3 (0.74) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL29699265 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL18766190 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8745753 | 0.82 | NQO1 (0.61) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Chromonar SCHEMBL29351852 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Chromonar SCHEMBL122836 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282764-A1 | IMIDAZOLE HETEROCYCLE BASED COMPOUNDS AND METHODS OF TREATING CANCER | KING ABDULAZIZ UNIVERSITY (SA) | 2025-09-11 | — | — | US | disclosed |
| US-11479536-B1 | Arylacetamides as AMP-activated protein kinase inhibitors and their use for treatment of breast cancer | KING ABDULAZIZ UNIVERSITY (SA) | 2022-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282764-A1 | IMIDAZOLE HETEROCYCLE BASED COMPOUNDS AND METHODS OF TREATING CANCER | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TTBK2, CDK13 | KDM4E 2443/4885ALDH1A1 1214/4885HPGD 1335/4885 |
| US-11479536-B1 | Arylacetamides as AMP-activated protein kinase inhibitors and their use for treatment of breast cancer | PRKAA2, PRKAA1, PRKAG2 | KDM4E 1837/4885ALDH1A1 1494/4885HPGD 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.