Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19028377 | 1.00 | BCL2L1 (0.48) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL3961093 | 0.82 | BCL2L1 (0.48) | BCL2L1BADDRD2DRD3DRD1 | |
| Bromide SCHEMBL384160 | 0.80 | BCL2L1 (0.47) | BCL2L1BADDRD2DRD3DRD1 | |
| Hydrochloric Acid SCHEMBL11569899 | 0.80 | BCL2L1 (0.47) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL30826977 | 0.72 | CD44 (0.61) | BCL2L1BADDRD2DRD3PNMT | |
| SCHEMBL29914246 | 0.72 | PNMT (0.67) | BCL2L1BADPNMT | |
| SCHEMBL3157785 | 0.72 | PNMT (0.67) | BCL2L1BADPNMT | |
| SCHEMBL1956718 | 0.72 | CD44 (0.61) | BCL2L1BADDRD2DRD3PNMT | |
| SCHEMBL9218467 | 0.72 | BCL2L1 (0.44) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL14247747 | 0.71 | BCL2L1 (0.38) | BCL2L1BADDRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306635-A1 | TDO2 Inhibitors | GENENTECH, INC. | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306635-A1 | TDO2 Inhibitors | TDO2, IDO2, IDO1 | BCL2L1 2392/4885BAD 1706/4885DRD2 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.