SCHEMBL2994562

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2984078	0.92	MAPT (0.42)	MAPTTP53THRBLMNAKDM4E
	SCHEMBL17354737	0.92	NPC1 (0.46)	MAPTTP53THRBLMNAKDM4E
	SCHEMBL2996552	0.92	KDM4E (0.46)	MAPTTP53THRBLMNAKDM4E
	SCHEMBL2984879	0.90	MAPT (0.52)	MAPTTP53THRBLMNAKDM4E
	SCHEMBL4151669	0.89	MAPT (0.40)	MAPTTP53THRBLMNAKDM4E
	SCHEMBL2991496	0.88	MAPT (0.39)	MAPTTP53THRBLMNAKDM4E
	SCHEMBL2996341	0.88	KMO (0.50)	MAPTTP53THRBLMNAKDM4E
	SCHEMBL2985640	0.87	MAPT (0.45)	MAPTTP53THRBLMNASERPINE1
	SCHEMBL2996787	0.86	MAPT (0.52)	MAPTTP53THRBLMNAKDM4E
	SCHEMBL2993560	0.86	PDE4D (0.43)	MAPTTP53THRBLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.